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BNF 81 (British National Formulary) March 2021


Available on back-order


The British National Formulary (BNF) is the first choice for concise medicines information. Trusted by healthcare professionals across the world to support confident decision-making at the point of care.
The new edition (BNF 81) provides up-to-date guidance on prescribing, dispensing, and administering medicines, plus legal and professional guidelines.

Extensive content updates in the BNF 81 edition include:

New monographs for:

Fetcroja ® [cefiderocol] for aerobic Gram-negative infections in patients with limited treatment options
Jyseleca ® [filgotinib] for rheumatoid arthritis
Myopridin® [pridinol] for central and peripheral muscle spasms
Nilemdo® [bempedoic acid] for primary hypercholesterolaemia or mixed dyslipidaemia in patients who have not responded adequately to other appropriate measures
Sunosi® [solriamfetol] for excessive sleepiness associated with narcolepsy
Veklury® [remdesivir] for COVID-19 in patients with pneumonia requiring supplemental oxygen
Zeposia® [ozanimod] for multiple sclerosis

New preparations:

Rybelsus ® [semaglutide]: oral formulation for type 2 diabetes
Spravato ® [esketamine]: intranasal spray for major depressive disorder

MHRA advice on:

Clozapine and other antipsychotics: monitoring blood concentrations for toxicity
Direct-acting oral anticoagulants (DOACs): reminder of bleeding risk, availability of reversal agents
Stimulant laxatives available over-the-counter: new measures to support their safe use
Cyproterone acetate: new advice and restrictions of use to minimise risk of meningioma
Insulins (all types): risk of cutaneous amyloidosis at injection site
Methotrexate once-weekly for autoimmune diseases: new measures to reduce risk of fatal overdose due to inadvertent daily instead of weekly dosing
Morphine and other opioids: new guidance to risk of dependence and addiction

Other significant changes include updated guidance on:

Influenza, Varicella-zoster and Haemophilus influenzae type b conjugate vaccine in-line with Public Health England recommendations
Management of venous thromboembolism
Management of uncomplicated gonorrhoea

BNF 81 is an essential publication, it provides you with:

Up-to-date information on prescribing, dispensing, and administering medicines
Authoritative, independent guidance on best practice enabling you to select safe and effective medicines
Information, you know you can trust for quality, reliability and independence
Everything you need at your fingertips, all in one book

The BNF79 is also still available now on SALE

We also have available BNF for Children please follow this link: